Abc pest control11/3/2022 ![]() ![]() We discovered that CRISPR-mediated inactivation of two larval midgut transporter proteins that act as receptors for Bt toxins caused a 15,000-fold increase in the concentration of Bt toxin needed to kill fifty per cent of larvae. We used CRISPR gene editing to clarify the genetics of resistance to Bt toxins in the cotton bollworm, one of the world’s most damaging pests. Better understanding of the genetic basis of pest resistance to Bt toxins is urgently needed to address this problem. However, widespread planting for the past two decades of crops genetically engineered to produce Bt proteins has spurred rapid evolution of resistance in pests. Insect-killing proteins from the soil bacterium Bacillus thuringiensis (Bt) are increasingly important as environmentally friendly alternatives to conventional insecticides. armigera is expected to reduce the likelihood of field-evolved resistance relative to disruption of a toxic process where mutations affecting a single protein can confer resistance. The functional redundancy of these two proteins in toxicity of Cry1Ac to H. The results here provide the first evidence that either HaABCC2 or HaABCC3 protein is sufficient to confer substantial susceptibility to Cry1Ac. In contrast with previous results, susceptibility to two insecticides derived from bacteria other than Bt (abamectin and spinetoram), was not affected by knocking out HaABCC2, HaABCC3, or both. Bioassays of progeny from interstrain crosses revealed that one wild type allele of either HaABCC2 or HaABCC3 is sufficient to sustain substantial susceptibility to Cry1Ac. Inheritance of resistance was autosomal and recessive. We discovered that CRISPR-mediated knockouts of ATP-binding cassette (ABC) transporter genes HaABCC2 and HaABCC3 together caused >15,000-fold resistance to Bt toxin Cry1Ac, whereas knocking out either HaABCC2 or HaABCC3 alone had little or no effect. Here we used CRISPR/Cas9 gene editing to clarify the genetics of Bt resistance and the associated effects on susceptibility to other microbial insecticides in one of the world’s most damaging pests, the cotton bollworm ( Helicoverpa armigera). ![]() Better understanding of the genetic basis of resistance is needed to more effectively monitor, manage, and counter pest resistance to Bt toxins. Evolution of pest resistance reduces the efficacy of insecticidal proteins from the gram-positive bacterium Bacillus thuringiensis (Bt) used widely in sprays and transgenic crops. ![]()
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Psychonauts 2 fungus11/3/2022 ![]() ![]() In Mesoamerica, they have been consumed in ritual ceremonies for 3000 years. 8.4 Hallucinogen-perception persisting disorder (HPPD)Ĭave art in Tassili n'Ajjer, Algeria (look at the shoulders and knees)Ī growing body of evidence suggests that psychoactive mushrooms have been used by humans in religious ceremonies for thousands of years.It is highly advised to use harm reduction practices if using this substance. However, adverse psychological reactions such as severe anxiety, paranoia, delusions and psychosis are always possible, particularly among individuals predisposed to mental disorders. Unlike most highly prohibited substances, psilocybin mushrooms have low abuse potential and are neither addictive nor physiologically toxic. They also are reported to produce slightly more emotion enhancement, time distortion and ego loss than the aforementioned substances, as well as more nausea, confusion, and sedation. In distinction to psychedelics like LSD, mescaline, and 2C-B, which may be described as "stimulating", "cerebral", and "bright", psilocybin mushrooms are typically described as having an "earthy", "subliminal", or "dream-like" quality. They are often described to evoke entheogenic, mystical-like, or transpersonal experiences that may facilitate self-reflection and personal growth. ![]() The intensity and duration of effects can vary greatly depending on factors such as species and batch, which can complicate standardized dosing information (see this section). Subjective effects include visual geometry, hallucinatory states, time distortion, enhanced introspection, conceptual thinking, euphoria, and ego loss. As a part of the so-called "psychedelic renaissance", they are currently being investigated in the treatment of a number of ailments including anxiety, depression, addiction, and other mental disorders. Today, they are among the most widely used psychedelic substances (partly due to the ease of personal cultivation and harvesting). Widespread usage of psychedelics provoked a societal backlash, and they were prohibited in 1970. Along with LSD, they were incorporated into the youth counterculture movement of the 1960s. Based on imagery found in prehistoric rock art, they are thought to have been used by various human cultures since before recorded history.Īfter being introduced to the Western world in the 1950s, they generated substantial public interest. Psilocybin mushrooms occur on all continents and have been taxonomically classified into over 200 species, the most potent of which belong to the genus Psilocybe. The mechanism of action is not fully known, although binding activity at serotonin receptors is thought to be involved. Psilocybin mushrooms (also known as magic mushrooms, psychedelic mushrooms, and shrooms) are a family of psychoactive fungi that contain psilocybin, a psychedelic substance of the tryptamine class. Psilocybe cubensis, one of the most common psilocybin-containing mushrooms. ![]() Macfamilytree resizing11/3/2022 ![]() ![]() There have been useable free/shareware programs that have helped but had none of the functionality of the PC based programmes. #Macfamilytree resizing software#Finding quality genealogy software for the Mac has been impossible. MacFamilyTree helps you capture your family history, and turns data and facts into conclusive reports and visually impressive charts. Explore your family tree and your family history in a way generations of chroniclers before you would have loved. MacFamilyTree 8 gives genealogy a facelift: modern, interactive, convenient and fast. ![]() ![]() Search the free FamilySearch archive, which contains billions. MacFamilyTree 9 offers you a wide range of options to capture and visualize your family history. Discover and experience your personal family history, explore your origins, your ancestors, and how your family has evolved over the course of time. MacFamilyTree offers numerous options for you to capture and visualize your family history. For those just starting out investigating their family history, it provides an easy way to visualize and share your family tree with photos, stories and basic facts about each person. Add media such as photos and videos, document places where significant events have occurred, and have fun with the way MacFamilyTree turns facts and figures into captivating history lessons. You can use it to build interactive family charts in no time at all. MacFamilyTree offers support and assistance across all aspects of genealogy from research through data entry to evaluation and visualization. My Family Tree™ is a genealogy application for Windows®. ![]() Star chart tonight11/1/2022 ![]() ![]() One interesting aspect is that Mars passes several stars three times – triple conjunctions. On October 30, the arrows start to pivot clockwise or westward until January 2023, when they turn eastward again. When Mars nears the Bull’s horns, the lines are nearly parallel, indicating that the eastward march slows. Beginning August 16, the first date on the chart, the lines appear to turn eastward or counterclockwise on the chart. Lines of sight are drawn from Earth through Mars toward the starfield for specific dates when the Red Planet appears near certain stars. On this annotated chart, the orbits of Earth and Mars are displayed. They would fall into the sun.Ĭhart Caption – 2022, October 30: This chart shows the relative orbits of Earth and Mars. There would be serious gravitational consequences if the planets stopped in their orbital motions. The planets do not suddenly halt their direction and backup. ![]() We see them appear against the background of distant stars, normally appearing to move eastward.Īs our planet catches and moves inside the slower-moving outer worlds, they appear to stop and move westward, an illusion. Recently, though, its eastward march has slowed and for several mornings it seems to be in nearly the same place compared to Zeta Tauri – the southern horn.Ī planet’s motion against the sidereal background is a combination of Earth’s and the planet’s orbital motions around the sun. Mars has been steadily moving eastward in front of Taurus for nearly three months. Sky watchers in urban and suburban may need a binocular to see Taurus. During the night it appears higher in the sky and by morning twilight it is high in the west-southwest above the Bull’s horns – Elnath and Zeta Tauri. The planet rises in the east-northeast 2.5 hours after sunset. Mars appears with many bright stars during this season. Chart Caption – 2022, October 30: Mars is above the horns of Taurus before daybreak.Įven with the bright appearance of Jupiter for most of the night, the spectacle of the autumn season this year is the opposition of Mars that occurs on December 7 th. ![]() Yusuke persona 5 royal11/1/2022 ![]() ![]() ![]() Your party members (Confidants) can’t learn new skills using the same methods. Only the Joker’s Personas can learn Skills using gallows, Skill Cards, and more. #Yusuke persona 5 royal how toHow to Use Skill Cards on Party Members in Persona 5 You can take the completed Cards back by talking to Yusuke after the duplication process finishes, but this process takes at least one day to complete.Ī temporary downside is that you can’t duplicate mid to high-tier Skill Cards right away as you will need to advance Yusuke’s Confidant Rank to 5 and 7 first. To replicate a Card, you need to give it to Yusuke along with a Blank Card. #Yusuke persona 5 royal freeYusuke will duplicate Skill Cards for you free of charge. The former lets Yusuke paint Skill Cards on Blank Cards for medium-end Skills, while the latter is for high-end Skills. However, you’ll need to reach Yusuke’s Confidant Rank 5 to unlock “Adept Duplication” and Rank 7 to unlock Master Duplication. At the beginning of his Confidant, Yusuke will learn the Skill Cards “Novice Duplication” process, making it easy to access. These abilities allow Yusuke to paint Skill Cards on Blank Cards. This feature is thanks to Yusuke’s “Novice Duplication,” “Adept Duration,” and “Master Duplication” Confidant abilities. You can duplicate Skill Cards you already possess by converting Blank Cards into Skill Cards through Yusuke Kitagawa. Aside from getting Skill Cards as a rare drop from enemies, you can force them to give Skill Cards to you.ĭuplicate Your Skill Cards Through Yusuke in Persona 5 Random steals and request rewards can also yield Blank Cards. Keep in mind that out of all the chests you can find in Persona 5, 23 of them are locked. Make sure to check every chest in a Palace if you go hunting. Once you unlock the maps of a Palace and walk past a chest, it will show on the map. You can find Skill Cards and Blank Cards in chests. Hence, his mobile shop is only accessible once you reach it. He appears randomly in Mementos, but the map will indicate his arrival by a cutscene of him driving close to the Phantom Thieves. Purchasing Blank Cards from a retail location named “Jose’s Shop” is another way to go. It includes one of each basic Skills such as Agi, Garu, Psy, Dia, Kouha, Tarukaja, Bufu, Frei, Zio, Eiha, Rakukaja, Sukukaja and three Blank Cards. #Yusuke persona 5 royal downloadAs outlined below, these Confidants also have deadlines attached to them, so prioritize them when you can.You can download the free Skill Cards DLC pack named “Skill Card set” for P5 and P5 Royal. These are all tied to characters who play major roles in the events of the new third semester, so it's important to level all of them. ![]() Persona 5 Royal features three new and critical Confidants: Councillor, Faith, and Justice. This ability is well worth it, because even a single high-level Persona can carry you through some tough fights.Ĭouncillor, Faith, and Justice for the third semester Once you raise the Strength Confidant a few levels, you'll unlock the ability to fuse Persona which are above your current level - in exchange for a hefty chunk of change, that is. You'll be able to make tools and read books in class, do laundry without blowing your evening, and even hang out with Confidants on days you explore the Metaverse. The Temperance Confidant will also save you time in the long run, letting you spend more time on Confidants and social stats and less time handling busywork. This won't actually level your Confidants, but it will cut out virtually all of those dreaded "just hang out to gain notes" sessions, which makes leveling multiple Confidants much easier. ![]() At Fortune level five, you unlock the ability to pay 5,000 Yen to instantly deepen your affinity with any other Confidant, and you can do this once a day. Fortune is the most valuable Confidant in the game. ![]() Garageband ringtone maker 2015 iphone11/1/2022 ![]() ![]() The file will look completely the same but that’s okay. You do actually know what you’re doing, so click on “ Use. MacOS will complain because it generally doesn’t believe we users are smart enough to know what we’re doing when changing suffixes, so you’ll get a message like this: You can change the suffix of a filename in MacOS X by just clicking and typing in a new suffix, however, so click twice (slowly) on the icon to be able to edit the filename, then add “.m4r”. By default, Quicktime Player saves audio files with an ‘.m4a” suffix, but we need something different to indicate to iTunes that it’s actually a ringtone. Once it’s exported, you’ll have a file on your Desktop with the name specified and, well, the wrong filename suffix. This is done by using the Export feature from Quicktime:Īs you can see above, choose “ Export As” -> “ Audio Only…” then specify a memorable filename that’s going to become your ringtone name. Now you’ll have a recording you can audition to ensure it’s what you want by pressing play: You’re going to click on the red record button in the middle, count to 5, then click on it again. If you just want silence, it’s probably good to be in a very quiet environment for the next step. If you want to actually record someone, have them nearby and ready to go. Launch it, then choose “New Audio Recording…” from the File menu:Ī little recording control window shows up: Much of the work is going to be done in the powerful but often overlooked Quicktime Player app. Like… your dog barking, or your baby laughing or your partner saying “honey, honey, honey, honey!” □ ![]() #GARAGEBAND RINGTONE MAKER 2015 IPHONE HOW TO#Fortunately, we know how to make our own and it turns out that the sequence is exactly the same if you want to record someone and use that as a ringtone too. So useful that it’s a surprise that it’s not one of the options included with iOS, actually. At this point I think I’m up to 20+ numbers in that contact, actually.įor this scenario and others where you don’t want to block someone (tho they don’t know you’ve blocked them) it’s useful to have a silent ringtone. What I do is drop all those numbers into a single contact I created called “Ignore Me” and if my phone rings, vibrates, my watch lights up, whatever, a quick glance confirms that it’s not anyone I need to bother actually answering. Then again, you might opt for a different strategy if there are a lot of numbers that seem to have you in rotation since as far as I can tell the cellular do not call list clearly isn’t working as I’m on it and I get 10-20 calls/day nonetheless. That sounds really annoying, no question! The easiest way to deal with it is to actually block their number, which you can do by going to your Recent Calls area in the Phone app, tap on the “i” adjacent to the call, then choose “Block this Caller”. ![]() ![]() ![]()
The pirates being the blighters they are, will fire back at you and cause damage to your ship, they will also throw ropes to climb across and place bombs on your deck. It takes a small amount of time before you’re able to fire your cannon again. To defeat the pirates, you are required to click on a cannon, this will send one of your crew to fire the cannon at the pirate ship. Your adventure begins with a Sea Battle, attacked by pirates you must defeat the pirates by destroying their ship, while repairing yours at the same time. This is how the story of Jack and his crew begins in a new land. They could already hear the bandits’ laughter. Suddenly, the crew noticed pirates pursuing them! Jack hurried to reach the land, but the pirate ship was too fast. After a long voyage, there was hope: according to the map, the shores of the New World were close. Brave Jack Savvy sailed to the Caribbean from England, eager to build his settlement and develop a successful business on fertile lands. You will find downloadable wallpapers and music, a step-by-step guide and the encyclopedia of Merchants of the Caribbean only in the Collector's Edition!.A normal mode for players familiar with casual games.An easy game mode with no limitations.Dangerous enemies: Magic Obstacles, Spirits and evil Totems.Dozens of unique achievements for experienced gamers.Lots of different tasks you have not yet encountered.Keep attention focused on the most important things, think over the strategy of each level and you will win! The products made there cost more at the local market. #Merchants of the caribbean collecters edition how toBesides, thanks to new technologies, you will learn how to build various processing facilities. OK, you managed to fight off the pirates! Then it's high time to explore new lands! The colonists will have to restore bridges and roads, clear debris and open chests with gold scattered across colorful locations. This is how the story of Merchants of the Caribbean begins! After a long voyage he finally saw the shores of the New World… Then all of a sudden, a pirate ship appeared on the horizon! Jack was hoping to quickly get ashore, but the pirate ship turned out to be too fast - just few minutes, and the laughter of the sea robbers could be distinctly heard. As a bonus, Collector's Edition purchases count toward three stamps on your Monthly Game Club Punch Card!Īs always, please remember to come back and tell us what you think.The XVI century, an Englishman named Jack Savvy is travelling to the Caribbean hoping to build his future trading empire there. #Merchants of the caribbean collecters edition fullThis is a special Collector's Edition release full of exclusive extras you won’t find in the standard version. ![]() Stake your claim in the New World in a swashbuckling adventure for every age! Defeat thieving pirates in thrilling ship-to-ship battles and employ your economic smarts as you coax a booming province out of the uncultivated lands! Are you prepared for the journey that lies ahead? Sailors, cannons and boundless courage are at your disposal, so place all hands on deck as you set out for excitement and success! Alawar Entertainment embarks on a high-seas adventure with Merchants of the Caribbean! ![]() Skinfold body fat calculator11/1/2022 ![]() SKINFOLD BODY FAT CALCULATOR MANUALAlways only measure the right side, in order to get a consistent result with any re-measurement. Since this calculator uses 9 sites to compute its result it tends to be much more accurate than other manual calculation methods like 3-site skinfold tests. With a seven-point measurement, body fat percentage is measured at seven different places. Supra-iliac fold– above the edge of the pelvis. ![]()
Soundsource alternative mac11/1/2022 ![]() ![]()
![]() There are several options for you to exit out of SoundSource: Before you start the uninstallation, you are supposed to quite the app if it is running, otherwise the uninstall may fail or trigger error message. What should you do before uninstalling SoundSource:įirst of all, don’t rush to drag SoundSource to the Trash. #Soundsource alternative mac how to#Struggling to uninstall unneeded applications from your Mac computer? Having trouble in removing the entire application components around the system? This tutorial will show you how to effectively uninstall SoundSource in macOS or Mac OS X. Once you do not want to keep an app on your Mac, you can uninstall SoundSource by multiple methods. #Soundsource alternative mac install#You can get an app from Mac’s App Store, discs or other websites, and then install it by dragging the app icon to the Applications folder or running the provided installer in the disk image or package file. #Soundsource alternative mac software#If you’re working on monitors or headphones and your ringtone jumps out at you like Marty McFly with his guitar at the beginning of Back To The Future you’ll know how useful it is to be able to control this and its only recently that it was pointed out to me that I can route FaceTime alerts through my Mac’s internal speakers and keep those alerts safely away from my interface.There are various kinds of software that you can install on your Mac, and it is quite easy to manage those apps on macOS. Try listening to the sides only of music on YouTube to really hear what data compression can do to music (yikes!).Ĭontrol the level of alerts, including phone calls! Anyone with an iPhone, and iPad and a Mac knows the pandemonium which erupts when someone phones you. You can of course import in to your DAW but why bother when you can just call up a plugin strapped across the output of your streaming service. Some music suits this treatment well and allows you to listen into the arrangements, the use of reverbs, the string or BV arrangements. If you don’t regularly listen to music you know and admire in mono or auditioning just the sides of the MS components, I recommend it. Using a plug-in to audition the MS signal or mono compatibility of records I like directly from Tidal using Nugen Audio’s Sig Mod. ![]() I’m not a fan of Systemwide, If you change your sound settings as often as I do I find it invasive. #Soundsource alternative mac pro#I’ll give you my three favourite uses:Īpplying Sonarworks Reference 4 speaker calibration to the output of Pro Tools at the system level without having to use Sonarworks Systemwide. This might sound gimmicky and while it could be used to route your browser audio through a flanger it is an invaluable tool which can be used to solve real issues. You can also apply processing including AU plugins on a per-application level. What SoundSource gives you is the ability to route each application to the interface of your choosing, at the volume of your choosing. You can set your DAW to use a particular interface in the playback engine of application sound preferences but fo systemwide sounds all you can do is pictured below. In the MacOS Sound Preferences you have limited control over what sound goes where. This is a big deal if you prioritise sound as much as we do. SoundSource takes the limited options available in the Mac OS Sound Preferences and makes them properly flexible. I’d been too busy thinking about groundbreaking plugins or revolutionary new workflows in DAWs to remember that in exactly the same way as I namecheck my sit/stand desk in my Hardware Product of 2020 article, it’s the things we use every day which make the biggest difference to our lives and considering my working life is spent mostly being distracted by messages and phone calls while working at my Mac, SoundSource from Rogue Amoeba has been an absolute lifesaver. While racking my brains for a an alternative I received a phone call and the answer presented itself inthe way the phone alert behaved on my computer. I was a little slow off the mark when we started writing these Product of 2020 articles and when I came to write mine I found that two of the products which came to mind immediately had been taken! I’ll leave exactly which those were to your imagination but I think anyone who follows the blog closely will probably guess pretty quickly. Rogue Amoeba SoundSource is Julian Rodgers’ Software Product Of 2020, he explains why. ![]() AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |